Q: Can I order DCA directly from DCA-LAB? If so, how do I place an order? William. A: Hello, William. If you want to order from DCA-LAB or other suppliers - please find their website links here: https://www.dcalab.com/ https://www.dcaguide.org/suppliers/ You can also find them on Amazon: https://www.amazon.co.uk/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Dichloroacetate Hope this is helpful.
Q: Is DCA successful in treating SCLC (small cell lung cancer)? Wayne A: Dear Wayne, thank you for your email. We have heard reports about people that successfully stopped SCLC (small cell lung cancer) progression with the help of DCA. One of them is in remission till this day and is still taking Sodium dichloroacetate for prophylaxis. However, as you have probably heard, SCLC is a really aggressive cancer and it needs the best measures to fight this disease. This means that DCA alone could still not be enough. If you haven't received a lot of nerve damaging chemotherapy and do not suffer from current peripheral neuropathy, you can consider trying DCA alone or alongside other cancer treatments. Just please don't stop your current health checkups by your doctor and follow his advice. A recent study has shown that DCA works well in combination with fenbendazole. (Ref.) There is also a growing community, which uses fenbendazole alongside conventional or alternative therapy to treat their cancer. Fenbendazole can sometimes do wonders when treating lung cancer. Give it a try. We advise you to try DCA in combination with fenbendazole for the best result. You can find more information on DCA usage here: DCA information. More information on fenbendazole and its potential therapeutic benefits for oncological diseases can be found here: https://www.fenbendazole.org/. The rest of the information can be found on google by using the keywords ‘‘fenbendazole cancer“. Hope this information helps.
Q: Can DCA be taken while fasting ? Or is it better to wait until the fasting is done ? I‘m on a 30 day fast.MarekA: Dear Marek, thank you for your question. DCA can still be absorbed while you are fasting. However, if you take DCA in powder form, dissolve it into a solution, drinking it on an empty stomach may cause heartburn after a while. The stomach that has had no food for longer periods of time can get irritated really easily. To avoid this, you should take Sodium dichloroacetate in a capsule form. This way it will be lighter on your stomach. Also, take lower doses when you’re on your fasting protocol. Taking 6,25-12,5 mg/kg daily should be great.
Q: Is your group still in existence? Do you have any information on DCA quality since 2018? Have you discovered who is behind "Certified DCA", whether it is really a pharmaceutical grade product, and whether its purity is as they claim? Elizabeth A: Dear Elizabeth, thank you for your email. Yes, our group is still in existence. However, due to the Covid-19 pandemic, we have been less active lately. We are still following the global situation on DCA manufacturing. Unfortunately, a lot of Sodium dichloroacetate suppliers have remained completely the same or have taken a step back in terms of the quality of their services. Many popular DCA suppliers have abandoned this molecule due to the recent inactivity of clinical trials with Sodium dichloroacetate. This was partly caused by the Corona virus pandemic, since all the attention and funding were redirected towards solving the Covid-19 crisis. Nevertheless, the situation should come back to normal in half a year. We noticed that a lot of previously great DCA sellers have developed problems with their sites, customer service quality and delivering the products on time. Regarding the claims by Certified DCA. Firstly, Sodium dichloroacetate is not registered as a licensed medicine, therefore a pharmaceutical grade product of DCA cannot officially exist. Such claims are false. Secondly, the quality of their product has not changed since the last time we reviewed them. Therefore, we didn't feel the need to update their product review. Lately, their site has been down and it’s not possible to order a new batch of their production. We’ll try to check them whenever it will be possible. Best regards, DCA Guide
Q: Dear Sir or Madam, I have a question about DCA, next week I start with immune therapy because I have lung cancer. Is it safe and can I still use DCA? Best regards, Alfredo. A: Dear Alfredo, thank you for your letter. We are getting similar questions often, therefore, we will try to explain DCA and immunotherapy in greater detail. In most cases, using Sodium dichloroacetate with checkpoint inhibitors such as pembrolizumab (Keytruda), atezolizumab (Tecentriq) and other similar drugs is a great option. It does not look that DCA could be unsafe with any type of immunotherapies. (Ref.) Immunotherapy helps the person’s own immune system fight against tumors. This class of medications is especially useful when the cancer develops resistance against conventional chemotherapy treatment. It also allows the immunity to bypass the special proteins that cancer cells develop as “camouflage” to continue growing and expanding. As the cancer progresses, it continues to develop an acidic environment around it. Lactic acid is considered an important factor in driving cell invasion, angiogenesis and immune suppression. Unfortunately, this process disables the immune system from fully engaging in tumor eradication. Furthermore, it diminishes the effectiveness of immunotherapy. The mechanism can be seen in the scheme below. (Ref.) It is proven that DCA successfully inhibits aerobic glycolysis in cancer. This decreases the massive amount of lactate secreted by the tumor cells and prevents acidosis. The surrounding extracellular space remains in normal pH, thus the immune system can recognize and destroy tumors more effectively. Considering everything, if you aim to efficiently treat cancer, Sodium dichloroacetate and immunotherapy can go hand in hand. These are the key points that you should keep in mind when using DCA alongside immunotherapy: • You should be free from peripheral neuropathy caused by previous chemotherapy treatment, • If you develop rare neurological complications from immunotherapy such as Guillan-Barre syndrome, encephalitis or any type of neuropathies, please stop DCA treatment until the side effects resolve, • Avoid using DCA, Vitamin B1 and Alpha-lipoic acid during your stay at the hospital while you’re receiving immunotherapy, you can resume DCA and supplements 2 days after you’re released from the healthcare setting, • If you’re receiving cytotoxic chemotherapy, such as platinum based compounds (cisplatin, carboplatin, oxaliplatin) or taxanes (paclitaxel, docetaxel) – avoid using DCA and Alpha-lipoic acid 3 days before hospitalisation and 7 days after receiving chemotherapy infusions. After that time period, if you haven’t developed chemotherapy induced peripheral neuropathy, you can continue using the DCA protocol as usual. Remember, DCA fights cancer on its own and can be used as monotherapy, but when it is incorporated with immunotherapy, the combination should work even stronger. (Ref.) Hope you find this information useful. Best regards, DCA Guide
Q: Can we use along with Keytruda/Pembrolizumab ? Jon D. A: Hello, Jon. Yes, DCA can be safely used with Keytruda (Pembrolizumab) as no drug-drug interactions are expected. (Ref.) As far as we heard from our own experience, there haven't been any bad interactions between Sodium dichloroacetate and biological therapy. Also, based on research and cancer biology facts, it seems that DCA and immunotherapy can go hand in hand. (Ref.) You can find more details in the previous answer that analyses Sodium dichloroacetate and immunotherapy in-depth. (32)
Q: My Dr. Gave me DCA capsules... 333 mg capsules to take 2-2x a day... I tried to take them, would get sick & throw up immediately... do you have any idea why this would be happening? Thank you...Sincerely. Troy B. A: Hello, Troy. The situation is rather strange. It could be due to the fact that your doctor was prescribing you with impure DCA. DCA can irritate the stomach mucosa. However, we've got the subject covered in our article: https://www.dcaguide.org/methods-and-supplements-for-preventing-dca-side-effects "On rare occasions, Sodium dichloroacetate administration can result in heartburn or nausea. If this is the case, try taking DCA after you eat a little bit of food and drink some fluids to avoid taking the medication on an empty stomach. If that didn't resolve the problem, you should try taking medications that lower gastric acid secretion - Proton pump inhibitors. Any type of PPI is acceptable provided the fact that they don't have any major differences. ▪ Pantoprazole / Omeprazole / Esomeprazole (take one 40mg tablet per day, at the same time. Take it at least 30 minutes before your meal and DCA.) For convenience purposes, we recommend using Pantoprazole because it doesn't seem to have any poor interactions with other medications. However, any other Proton pump inhibitors should have the same effect. Let us know if you have any more questions.
Q: Hi, I was just wondering if DCA can help with MS at all? Thanks Claire A: Hello, Claire. Unfortunately, there have been no significant studies regarding DCA usage for Multiple sclerosis. We also can't confirm that DCA mechanism could revert the damage MS does to the nerves. As far as our limited knowledge enables us comment on the subject, your best bet would be to use glatiramer acetate + B - interferon (this is a classical choice). The following years were interesting on many disease therapies, as the biological therapy agents have shed light on many disease treatments. Fingolimod (Gilenya) and Dimethyl fumarate seem to be promising new agents that can slow down the progression of Multiple sclerosis. Campath, Rituximab and Ocrelizumab are promising new approaches towards MS. Consult your doctor on the subject. A neurologist would be your best bet. From our personal experience, we have seen people who have regained their ability to walk and live a better life with the help of specific rehabilitation procedures for MS.
Q: My sister has advanced hormone receptive breast cancer with extensive liver mets. We’d like to try DCA, my only concern is as her liver isn’t in a great way is it safe to take? My worry is liver failure. Unfortunately, we can’t get it via IV in the UK. I’d be greateful for any information. Kind regards, Reena T. A: Hello, Reena! Is your sister on Tamoxifen? (If yes, read this article - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312350/. Tamoxifen + DCA can have a synergistic effect) From our narrow knowledge, we haven't encountered anyone who took DCA and experienced liver problems. However, I would approach this treatment option with relative caution and maybe try lower than medium doses due to existing liver damage. There have been no deaths related to DCA usage and you can find all of the side effects in this article: https://www.dcaguide.org/dca-safety-and-side-effects.This is what we've the article mentions regarding DCA and liver function: ▪ Mild liver enzyme (AST, ALT, GGT) elevation, without symptoms. A majority of medications can cause mild liver enzyme changes in the blood. DCA can cause minimal liver AST,ALT, GGT elevations (about 50 – 60 U/l) for 1 % of the patients. These little alterations should not cause any worries. A more acute and bigger liver enzyme increase can be caused by antibiotics, Tyenol/Paracetamol (acetaminophen), certain types of medicinal herbs and birth control pills. (Ref.) ▪ DCA and the liver. In case of liver failure and severe jaundice don’t use high doses of DCA, because Sodium dichloroacetate is metabolised in the liver. In situations like these, DCA should be administered intravenously and not through the mouth. If the patient experiences AST and ALT or bilirubin elevation by 150% from the upper reference norm, a pause should be made (Ref.)" If I was in your situation, I would check her liver function with liver enzyme blood test. I wouldn't take DCA if AST or ALT were higher than 100 U/l. Elevated Bilirubin can also be a red flag in this situation. All in all, she could use the oral form DCA orally, just in lower quantities, such as 10 - 20 mg/kg DCA daily. I/V DCA injections are difficult to find in the UK and are mostly given in Canada and Germany. We hope we shed some light on your question.
Q: I am wanting to use DCA with my cats as well, one who is being tested for possible lymphoma. Do you have any recommended dosages for pets/animals, or can I just use the dosage calculator and plug in their weight (10-15 lbs.)? Thank you so much for your website. It is greatly appreciated. Jason B. A: Dear Jason, thank you for your kind words. Unfortunately, we do not have a lot of information on scientific literature, which discusses cancer treatment in cats. We would recommend you to not exceed 10 mg/kg of DCA. Start by giving your pet half of the recommended dose (5 mg/kg). If she tolerates the medication without any visible side effects, increase the dose to 10 mg/kg after 21 days. The schedule should be 14 days on, 7 days off (for flushing out the excess DCA). Once done, repeat the cycle. Your best bet would be to order it from Amazon or to check our listed suppliers. DCA at Amazon: https://www.amazon.com/s?k=dca&ref=nb_sb_noss These DCA suppliers ship to Canada without bigger problems: DCA-LAB Sigma-Aldrich Pharma DCA
Q: Good Day, my Aunt has stage 4 colon cancer with metastasis. She is 5'7 and is weighing 140 pounds. Do you recommend starting DCA treatment and if so what dose should she take? Thank you. Isabel. A: Dear Isabel, thank you for your question. DCA therapy can help in almost every case of cancer, with varying degrees of success. The majority of people experience improvement in their symptoms, some have their disease stabilized and live without further cancer progression, and some even achieve remission thus remaining cancer-free. Nevertheless, stage IV colon cancer means that the tumors have spread in the body, this could make the treatment more difficult. Despite that, a clinical case published by Dr. A. Khan displays that DCA can be great for treating advanced colon cancer even when traditional medical treatments fail. You can read the study here: Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy. In the example of this 57-year-old woman, the stage IV colon cancer was stabilized with the help of Sodium dichloroacetate therapy and did not progress. It also did not cause any serious toxicity in the period of 4 years. The female remained highly functional and could continue running her own business, which proves that DCA treatment can be less debilitating than traditional chemotherapy. We could go on and on about the potential benefits of the Sodium dichloroacetate. To answer your question, we would recommend your aunt trying DCA. She can take it as a single treatment or combine it with the traditional chemotherapy (5-fluorouracil, oxaliplatin or irinotecan etc.) or immunotherapy (Avastin/bevacizumab). You can take DCA with Avastin without taking any breaks. However, when you‘re receiving chemotherapy – please make a two day break from DCA and Alpha-lipoic acid before getting chemotherapy and a three day break after receiving chemotherapy. Afterwards you can resume to taking the DCA protocol as usual. For your aunt, weighing 140 lbs, she should begin with 12,5 mg / kg a day. Take it for two weeks then do a one week break. This would mean that she takes one of the following: 1) 800 mg of DCA powder, 2) two 333 mg capsules with breakfast and one 333 mg capsule with dinner, 3) one 500 mg capsule with breakfast and one 500 mg capsule with dinner. If she tolerates DCA without any problems, she can move up to taking 25 mg / kg a day. Take it for two weeks, then take a week off. Repeat the cycles. Take one of the following: 1) 1600 mg of DCA powder, 2) three 333 mg capsules with breakfast and two 333 mg capsules with dinner, 3) two 500 mg capsules with breakfast and one 500 mg capsule with dinner. Don‘t forget to take the advice and supplements we describe here. Don't forget to take Vitamin B1 and Alpha-Lipoic acid with DCA just like we described. From our experience, we can tell that this is the biggest mistake some people tend to make. Here…
Q: Where is this drug made? Where can I get some? Thank you, Maureen R. A: Hello, Maureen. The drug is made in various places. Some manufacture it in China and other suppliers resell it, some produce it in Europe, some of the DCA is made in North America. The quality of each product differs, we recommend you checking all of the available suppliers below: https://www.dcaguide.org/suppliers These are the quality analysis we have done: https://www.dcaguide.org/dca-quality-analysis If you have some understanding of chemistry, you can check out the chemical analysis of each different brand DCA. Anion chromatography charts of every available product: DCA-LAB Sigma-Aldrich Pure DCA Pharma DCA There are some options available on Amazon.com, most of the products here are trustworthy: https://www.amazon.com/s/ref=nb_sb_noss?url=search-alias%3Dindustrial&field-keywords=dca Avoid buying Sodium dichloroacetate that has a higher impurity percentage as these impurities tend to be harmful and can cause new problems if used for prolonged periods of time. Clean, high-grade DCA can be used for years without any worries, provided that you follow the correct dosing rules and administration times.
Q: I mixed 1 (100 gram) bottle with 4 and1/4 cups of water. Now I have a 265 lb male which is x 9.09=2417.mg per day. The sry get only has ml or tsp how do I know how may ml to take each day. Kordy A: Hello, Kordy. Please read our article https://www.dcaguide.org/dca-dosage-and-usage-long-guide carefully. Look at "The usage of DCA powder and capsules". You should mix a 100 g of DCA powder with 980 ml of water. Then you get a solution in which 1 ml has 100 mg of DCA. If your dosage is 2400 mg per day, take 24 mililitres of the solution. Here‘s a detailed video on how to do it: https://www.youtube.com/watch?v=5kZaw0U84Wk
Q: Have you had proven positive results for AML? Leah A: Hello, Leah. Yes, however, these people that had AML also took traditional chemotherapy. Acute myeloid leukemia is an aggressive cancer that needs to be closely monitored by doctors, because it can cause anemia (which makes you weak), trombocytopenia (which makes you prone to bleeding) and, most importantly, it causes an impaired immune response (which makes you prone to catching infections). Therefore, we strongly advise every sufferer of acute myeloid leukemia to be monitored by their hematologist. Theoretically, DCA should be beneficial for every type of cancer. In some cases, drugs such as DCA can help you maintain a longer remission. Some medications like fenbendazole can mix pretty well with Sodium dichloroacetate in order to maintain a cancer-free time period. Sometimes, DCA can be the missing puzzle in the previous treatments that can finally help someone with AML achieve a lasting remission. The study explains instances like this in more detail: Perturbation of cellular oxidative state induced by dichloroacetate and arsenic trioxide for treatment of acute myeloid leukemia. Patients that cannot receive cytotoxic chemotherapy or have relapsed from remission could indeed benefit from the treatment of DCA. Blood cancers are a difficult subject, however, we hope that our answer sheds more light on your journey. Please don't hesitate to ask us more in case you have more questions.
Q: Hi, I wonder if any of the top rated DCA suppliers listed on your website can directly ship sodium DCA to mainland China. My aunt has been diagnosed with glioma three months ago, but her family refuses to use surgery or chemotherapy due to the concern over cost, lack of efficacy and severe side effects. She tried radiotherapy but the radiotherapy doesn't work well. So we thought to give DCA a try. Much appreciated if you can help me with my request. Thank you. Dan A: Hello, Dan. Yes, we believe that most of the listed DCA suppliers should be able shipping directly to China. The top two suppliers get orders from all over the world, including India, South Korea, Japan and so on. You can also try ordering it at Amazon: https://www.amazon.com/s/ref=nb_sb_noss?url=search-alias%3Daps&field-keywords=dca. We're glad that you've found this alternative solution, because we‘re aware of the limited choices today for treating gliomas. The most important clinical research on DCA for astrocytomas and glioblastomas discovered that Sodium dichloroacetate can be combined with all types of the possible treatments – surgery, radiotherapy and chemotherapy (in particular with Temozolomide). DCA is perfect for treating brain tumors as it is small enough to cross the blood-brain barrier and is truly safe in comparison with other treatments.
Q: Hi, I was interested in knowing if these studies are still being done in 2018 and if so how can one become a part of these studies. Donyale A: Hello, Donyale. We are certain that a lot of studies related to DCA are still being continued till this day. However, clinical research that aims to try out DCA on people diagnosed with cancer is performed more rarely. Such studies require a lot of funding to sponsor the hospitals as well as doctors in order to participate in them. Since Sodium dichloracetate is a generic drug and no pharmaceutical company can exclusively make profit from their investment in further research, it‘s a little bit harder to find new clinical trials that are searching for participants. Nevertheless, there have been numerous clinical trials performed in the past. You can also find dozens of clinical cases that showcase successful DCA therapy on cancer patients. You can find these papers in our page: "DCA research". If you would like to participate in such studies, your best bet would be to contact an oncologist, which is familiar with Sodium dichloroacetate.
Q: Taking DCA 2 week on with 1 week off I understand... How long term can a person take the DCA, 6 months, years ? Kreuzman. A: Dear Mr. Kreuzman, thank you for your question. There are no official guidelines on how long DCA can be taken. Regarding safety, there have been documented reports of people taking DCA for more than 4 years (https://www.dcaguide.org/news/dca-and-cancer-melanoma-long-time-remission-and-stabilisation-case-presentation-101258). In some clinical studies, children have taken DCA for even longer periods of time. If someone has stage IV cancer which has spread, then DCA and other regimens should be taken as long as possible to keep cancer stabilized or cured. How long can a person take Sodium dichloroacetate also heavily depends on how well the patient tolerates the DCA protocol, whether there is any preexisting liver failure or previous nerve injury. Diabetes can also cause nerve damage, therefore, preexisting diabetic neuropathy should be treated as much as possible before continuing the Sodium dichloroacetate treatment. Some people take it for years to keep themselves in remission. Our suggestions for longer time periods would be: • Stop taking DCA if you experience side effects. You can resume once they resolve. • Stop taking DCA if you have severe chronic liver failure, acute hepatitis, chemotherapy-associated liver injury. You can resume DCA once the liver is in better function. • Stop taking DCA if you experience abnormal liver enzyme (AST, ALT, GGT) elevation 2.5 times from the upper limit of normal levels. Take 1) silymarin or milk thistle, 2) essential phospholipids. Take a break till the liver enzymes return to normal levels. • Take DCA till you treat cancer or you want to maintain remission. Please don't forget to take the neuroprotective supplements such as Vitamin B1, Alpha-Lipoic acid and, if possible, Acetyl-L-Carnitine.
Q: Hello. So is dcalab.com selling verified high purity DCA by an independent lab? Is it safe to take? Thanks. Dan A: Hello, Dan. As far as we know, their DCA is of high quality. Over >99% pure. Their product has also been used in a couple of clinical trials with patients: 1) A pilot study done by Prof. F. Comhaire in Belgium on treating myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) with Sodium dichloroacetate (link), 2) A phase II clinical trial done by the University of Edinburgh using DCA as a possible treatment for endometriosis-associated pain (link). There is a quality comparison analysis on our site where we compare the most popular DCA suppliers. You can find a detailed quality analysis of each brand. The method of anionic and gas chromatography was used to get the results: https://www.dcaguide.org/dca-quality-analysis. We gave the maximum rating to two suppliers: -DCA Lab (they're an independent laboratory that specializes solely on high quality synthesis of Sodium dichloroacetate), -Sigma-Aldrich (they're a big company in Germany who manufactures a lot of chemical compounds. Their DCA is also of high quality. However, it is often hard to place an order). DCA LAB is also listed on www.molbase.com, which states that their product is 99.9% pure. Based on this information, we believe that DCALab.com offers high purity Sodium Dichloroacetate that is verified. They also have great customer support. Nevertheless, DCA is safe to take in most of the cases. On the other hand, 95-97% pure DCA can have synthesis byproducts such as Sodium monochloroacetate, which can be toxic. Therefore, we advise you to choose a verified supplier and to avoid online shops like https://www.alibaba.com/ for your own safety.
Q: Hello, I would like to purchase from DCA Lab as it is quite a good price compared to others. However I want to make sure that it is ok for human consumption. I heard some places use toluene or other chemicals to purify which is of course dangerous to humans and I just want to make sure that even though they are cheaper it can be used for humans and if you guys have experience with this company and others using their products. Thank you, Farzad A: Hello, Farzad. DCA is mostly sold as a lab chemical worldwide, because it is currently not registered as a drug or a food supplement. However, this could happen any time soon. It is considered as an alternative cancer treatment in Canada for example. You can read more in this document: http://www.oicc.ca/uploads/dca-health-professional.pdf. Regarding your question about DCA Lab, we have never asked them if they use toluene or other harmful chemicals. Nevertheless, we do believe that they have developed a safe technology, which enables them to synthesize great quality material. Their products are used in clinical trials with patients, therefore, it‘s safe to assume that they are legitimate. We know dozens of people who are taking their Sodium dichloroacetate and we have never heard that anyone experienced any complaints related to harmful chemicals in their products. Please also check this analysis we have made about the available DCA products to get a better idea on the global situation: https://www.dcaguide.org/dca-quality-analysis. In the analysis, look at the anion and gas chromatography tests. They confirm that no toluene has been detected in DCA Lab products. Every DCA seller should provide a certificate of analysis, which proves the purity of their product. DCA Lab is one of suppliers that provide CoA‘s with their production. Sigma-Aldrich and Tocris also produce exceptional quality Sodium dichloroacetate. Please consider them also. Avoid buying Sodium dichloroacetate that could have large quantities of impurities as these could be toxic if used for a longer period of time.
Q: What is the beginning daily dosage of DCA for a person weighing 220lbs? (BMI ideal weight 183-185bs)? How much Vitimin B1 and how often? Thank you, Charles. A: Hello, Charles. All of your answers are also answered in these pages: DCA dosage and usage (Long guide) and Methods and supplements for preventing DCA side effects . However, we will give you additional clarification on your specific situation. For someone who is 220 lbs, first try out 15 mg/kg. This mean should start with 1500 mg daily. For the first cycle (two weeks on, one week off) take 1500 mg of DCA (750 mg after or with breakfast and 750 mg after or with dinner). Take this for two weeks and then stop taking DCA for one week. Then, if you feel okay after the first cycle, move on to a larger dose: 25 mg / kg. Take DCA 1000 mg two times a day: 1000 mg with breakfast, 1000 mg with dinner. Don‘t forget to take Vitamin B1 (thiamine) three times a day: 100 mg in the morning, then 100 mg with lunch and 100 mg at dinner. If you can get hold of benfotiamine (a better version of Vitamin B1), take it in the same fashion, but 150 mg in three divided doses. It would be great if you could add Alpha-lipoic acid to your plan. Alpha-lipoic acid - take 300 mg with breakfast, 300 mg with lunch and 300 mg with dinner (total 900 mg daily). As with Vitamin B1, take it every day with no breaks. Consider adding L-Carnitine to your DCA regimen. Your total plan should look like: 1) DCA 1000 mg two times a day: 1000 mg with breakfast, 1000 mg with dinner. Take it daily for two full weeks, then take a break of one week. Repeat. 2) Vitamin B1 (Thiamine) - take 100 mg with breakfast, 100 mg with lunch and 100 mg with dinner. Benfotiamine is an even better form of Vit. B1 if you find it (then take 150 mg divided in three parts daily). Take every day, with no breaks. 3) Alpha-lipoic acid - take 300 mg with breakfast, 300 mg with lunch and 300 mg with dinner (total 900 mg daily). Take every day, with no breaks.
Q: For stage 4 it recommends DCA to be taken constantly. Does this mean without breaks? For how long? I'd guess until markers are normal and there is no need to continue. Or do you recommend continuing as a preventative? Please clarify. Thanks, Dana A: Dear Dana, it means that you still need to take breaks, otherwise peripheral neuropathy can ''kick-in" more swiftly and prevent you from using DCA for cancer prevention as soon as you‘re in remission. If one has stage IV cancer, the treatments that are given by the oncologist should also be continued. Most of the time, it will be chemotherapy, target therapy or immunotherapy. DCA goes well with most of these treatments, however, it goes especially well with target therapy and immunotherapy. A lot of cancers develop some sort of resistance to chemotherapy after its given frequently. Please understand that the main goal of treating stage IV cancer is transforming it into a chronic disease and prevent it from causing further harm through metastastis and growth. To achieve this, someone with stage IV cancer should constantly take some kind of anti-cancer treatment and monitor his health as well as tumors as a routine. Therefore, take DCA as a single agent or in combination with other methods to prevent cancer from spreading and getting larger. This means taking it for the rest of your life. Sometimes you develop any side effects such as peripheral neuropathy, which will make you to take a pause until they resolve. After they‘re gone, resume the DCA protocol. Cancer markers are one of the main ways to follow the progress / regress of the tumor advancement. The most accurate tumor markers that correlate with the size of the tumor are – 1) CA-125 (for ovarian cancer), 2) PSA (for prostate cancer) and 3) CEA (for colon cancer). You can repeat them every 3 months to see how well is the cancer responding to treatment. If they drop, it means that the malignancy is shrinking. One must also have imaging scans performed, to see if tumors are decreasing or increasing in size and to make sure if all the metastasis are gone. If you achieve remission, you can lower your DCA doses. DCA can be used as a preventative for cancer relapse if desired. Most of the cases take in doses lower than before, at least 50-80 % of the original dose that helped you achieve remission. Don’t forget that you can combine DCA with other natural methods or regimens that prevent cancer.
Q: Hello, my dear wife has been struggling with breast cancer and this site has been a great ray of hope. She has recently been put on a drug called Kisqali (ribociclib). Does anyone know if it is compatible with DCA? Or even complimentary? Do you know of any clinics/practices in Australia competent in administering this drug? I look forward very much to hearing from you. Richard. A: Hello, Richard. Unfortunately, Ribociclib (Kisqali) is quite a new therapy against breast cancer and we have found no studies, which discuss of combining it with DCA. However, we've reviewed the pharmacodynamics and pharmacokinetics of Ribociclib and it doesn't look like it should interact badly with Sodium dichloroacetate. In fact, as mentioned before, we have no bad experiences of combining DCA with targeted therapies. Please read carefully our work at DCA Information and learn all you need before administering DCA to your wife. Everything should be fine. Just don't overdose the DCA and remember that the protective supplements that we recommend with the DCA protocol are obligatory. DCA + Kisqali shouldn't cause any problems when used together. In fact, they could both provide benefits. Another therapy for breast cancer, Tamoxifen, has a synergistic effect with DCA. If you want real professional help, please contact Dr. Akbar Khan. He has a cancer center in Canada. He's one of the most famous oncologists who uses DCA with other conventional cancer treatments. We doubt that there is someone better in this field than him.